Embryo Update – The Results Are In!

Y’all, let me just start off by saying it has been a crazy few weeks! We actually got the results from our PGT-A testing a couple weeks ago, but I have been so busy with life, I haven’t had time to share them. I have to admit, though, all of those distractions have been most welcome as they keep my mind occupied so I don’t have time to dwell on things beyond my control. So, without further ado…… despite being told that it would take two weeks minimum for our results to come in, a week after the biopsy I got a call from our doctor while I was at work. ALL THREE EMBRYOS ARE CHROMOSOMALLY NORMAL!!!!!! When she told me that, I legit could not stop crying the happiest tears. I was expecting zero to one embryo to be normal. It didn’t even seem possible that all three would be normal simply based on our track record on this journey, yet here we are! It is such a relief knowing that we have these three little embabies in the freezer once we’re ready for them (plus the untested embryo from our second retrieval). Such a massive win for us!

So What’s Next?

At this point, we are doing a mock transfer cycle in preparation for the endomeTRIO tests (ERA, Emma, and Alice). Just like our most recent retrieval cycle, this cycle has not come without some bumps in the road. When we started prep for this cycle, we had in mind to follow the same protocol has our previous frozen transfer which involved daily Lupron injections (worst medicine ever) followed by intramuscular Progesterone in Oil (PIO) injections. Well, I started the Lupron about three days after our retrieval and my cycle started three days later (a week earlier than it was supposed to). Or at least I thought it did. When I went in for my baseline bloodwork and ultrasound, we found that my estrogen and progesterone were still elevated from the cycle before, so I was instructed to come back in that Friday for baseline try #2. On Friday, I went back in and, lo and behold, my estrogen and progesterone were still elevated! Conveniently, we had an appointment scheduled with our doctor to discuss the results of our retrieval and PGT-A testing. During this appointment, we discussed what was currently going on with my wacky hormones. Our doctor’s theory is that my body was so overloaded with hormones, it just needed a break. In light of that, she changed up my protocol for our mock cycle, and in turn, our next transfer cycle. She told me to stop the Lupron, which was the most welcome change I could have ever hoped for. (For those who have never taken Lupron, it’s the devil’s medicine. It gives me terrible migraines that do not go away regardless of what I do, and also causes terrible fatigue and brain fog.) She decided that we are, instead, going to try what is called a modified natural cycle. This means that I take minimal medications, and allow my body to just do its thing up until ovulation. Before my body has a chance to ovulate on its own, we will actually use an HCG trigger shot to induce ovulation. The reason we want to induce ovulation is to have some control over the timing of the luteal phase of my cycle. After ovulation, I will do the intramuscular PIO injections. Unlike a transfer cycle, instead of going in for the transfer after a few days on PIO, I will go in and they will take a sample of my uterine lining and send it off to the lab to have the endomeTRIO done. As a reminder from my previous post, this test will tell us exactly how many hours of progesterone I need for my lining to be receptive, as well as test for healthy bacteria and any infections that might be occurring inside my uterus. These results should take about 2-3 weeks to get back. God willing, we will be able to squeeze a transfer in before Christmas (the last day they will do transfers before the holidays is December 23, so fingers crossed)! The day after our appointment with our doctor, I had a third baseline monitoring appointment and, thankfully, both my estrogen and progesterone finally went down to where they should be at the beginning of a cycle. At this stage, I am just going in for monitoring appointments so we know when to trigger ovulation. Stay tuned for more updates to come on this rollercoaster journey!

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